Drug and Therapeutics Bulletin 1997;35:9-11; doi:10.1136/dtb.1997.3529
Copyright © 1997 by the BMJ Publishing Group Ltd.

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Generic medicines - can quality be assured?

Generic prescribing is steadily increasing, a change which we1 and others2–4 encourage. The proportion of prescriptions written in general practice in England using the generic (approved) name increased from 35% in 1985 to 55% in 1995.5 Where a product is prescribed generically, the alternatives that could be supplied should be equivalent, to ensure that patients are not put at risk. In this article, we review how the equivalence and quality of generic drugs are assured and consider whether the process is adequate.




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A. S. Kesselheim, A. S. Misono, J. L. Lee, M. R. Stedman, M. A. Brookhart, N. K. Choudhry, and W. H. Shrank
Clinical Equivalence of Generic and Brand-Name Drugs Used in Cardiovascular Disease: A Systematic Review and Meta-analysis
JAMA, December 3, 2008; 300(21): 2514 - 2526.
[Abstract] [Full Text] [PDF]



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© 1997 BMJ Publishing Group Ltd.