Drug and Therapeutics Bulletin 1997;35:33-36; doi:10.1136/dtb.1997.35533
Copyright © 1997 by the BMJ Publishing Group Ltd.

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{blacktriangledown}Moxonidine for hypertension

Relevant BNF section: 2.5.2

Moxonidine (Physiotens-Solvay) was introduced last year as the first of a new class of centrally-acting antihypertensive agents, the selective imidazoline receptor agonists. The manufacturer claims that moxonidine "accurately targets imidazoline receptors at the cardiovascular control centre in the brainstem" and is "as effective as current first-line therapies for essential hypertension". Other claims suggest that it causes fewer unwanted effects than older centrally-acting antihypertensive drugs such as clonidine and methyldopa. Is moxonidine a useful addition to the growing number of antihypertensives on the market?






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© 1997 BMJ Publishing Group Ltd.