Uncommon knowledge

Statins are of unquestioned value in the prevention of cardiovascular events and are used by increasing numbers of people. However, when new data emerges on their unwanted effects, it is essential that it is incorporated into product information. Our editorial this month questions why this has not happened in relation to the knowledge that statins can cause depression.
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Aspirin for primary prevention of cardiovascular disease?

Worldwide, many people take aspirin daily in the belief that doing so helps to prevent cardiovascular disease (CVD). However, there has been some uncertainty about the place of aspirin for the primary prevention of cardiovascular events. This article considers the place of low-dose aspirin in primary prevention of CVD.
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Over-the-counter weight loss with orlistat?

Orlistat first became available around 10 years ago as a prescription-only treatment for obesity. Earlier this year, orlistat 60mg capsules became available for sale to the public without a prescription and can now be purchased in the UK over-the-counter from pharmacies. The pill claims to "boost weight loss by 50%". This article reviews its place in tackling obesity.
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Management of seasonal affective disorder

Low mood associated with a certain season (usually winter) is very common. For example, in the UK, up to 6% of adults have "recurrent major depressive episodes with seasonal pattern", commonly known as seasonal affective disorder (SAD). This article discusses the management of adults with SAD, and in particular the use of light therapy.
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